SELENIUM
contributes to the protection of cells from oxidative stress and to normal spermatogenesis.
Why Sermatrop Alfa?
Sermatrop Alfa is a patented complex of scientifically substantiated microelements, antioxidants, phyto-extracts and amino acids. Sermatrop Alfa is designed for men aiming to maintain regular spermatogenesis and reproductive function. Due to its unique composition, Sermatrop Alfa has a complex effect. The antioxidants present in Sermatrop Alfa reduce oxidative stress via the enzymatic and non-enzymatic antioxidant defense mechanisms.
Sermatrop Alfa complies with all the applicable European quality standards.
Sermatrop Alfa is manufactured in France, is ECOCERT and ISO 22000:2005 certified. Product has 13 active ingredients which are exclusively produced in the EU, USA and Japan. All ingredients of Sermatrop Alfa complies with highest quality standards.
Sermatrop Alfa is convenient
to use – it is taken only
once per day
The benefits of the elements
in Sermatrop Alfa
ZINC
contributes to the protection of cells from oxidative stress, to normal DNA synthesis, to the maintenance of normal testosterone levels in the blood and has a role in the process of cell division.
FOLIC ACID AND VITAMIN B12
have a role in the process of cell division.
VITAMINS C AND E
contribute to the protection of cells from oxidative stress.
VITAMIN C
as well as vitamins B6 and B12 contribute to normal energy-yielding metabolism.
PHYTO-EXTRACTS AND UNIQUE SUBSTANCES
Phyto-extracts: Allium sativum and lycopene. Unique substances: N- acetylcysteine, glutathione, coenzyme Q10 and L-carnitine.
Scientifically-Based Unique Composition of Sermatrop Alfa
Glutathione, N-acetylcysteine, Selenium and Zinc are substances necessary for normal functioning of the enzymatic antioxidant defense mechanism. Vitamin C, vitamin E, vitamin B6, vitamin B12, Folic acid, L-carnitine and Lycopene are proven to strengthen antioxidative defenses in sperm thru non-enzymatic pathways. Scientific researches have shown that substances such as Coenzyme Q10, Selenium and Glutathione decrease activity of metalloproteinases.
Scientific studies have shown that Allium sativum extract, lycopene and N-acetylcysteine reduce inflammation. Sperm DNA integrity can be improved by reducing oxidative stress and inflammation, which is especially important when undergoing artificial insemination procedures.
| Active ingredient | 1 tablet contains |
|---|---|
| Vitamin C | 180 mg |
| L-carnitine | 100 mg |
| N-acetyl-cysteine | 60 mg |
| Vitamin E | 30 mg |
| Coenzyme Q10 | 22 mg |
| Zinc | 15 mg |
| L-glutathion | 12 mg |
| Allium Sativum | 8,34 mg |
| Lycopene | 7 mg |
| Vitamin B6 | 3 mg |
| Folic acid | 400 µg |
| Selenium | 80 µg |
| Vitamin B12 | 3 µg |
Convenient to use
Sermatrop Alfa is convenient to use as, differently from many other products, it is taken only once per day. The recommended course of administration of Sermatrop Alfa is 3 months, i.e. during the entire spermatogenesis process. However, clinical research data have shown that patients with higher need for microelements and antioxidants (selenium and zinc) may extend the duration of use up to 6 months.
Do not exceed the recommended daily dose.
Sermatrop Alfa is a dietary supplement. Sermatrop Alfa should not be used as a substitute for a varied diet.
Product should be stored out of the reach of young children.
Varied and balanced diet and a healthy lifestyle are very important.
Useful references
- Y.Zhang, J.C.Trussell, K.R.Chohan. Detecting and Minimizing Sperm DNA Damage. Semin Reprod Med., 2013
- JL Fernandez. Sperm DNA integrity and male infertility: current perspectives. Arch Med Sci., 2009
- E, Kruse. Relationship of seminal plasma IL8 and IL6 with semen quality. Hum Reprod, 2001.
- C, Wright. et al. Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility. Reprod Biomed Online, 2014.
- M Fraczek and M Kurpisz. Inflammatory mediators exert toxic effects of Oxidative stress on human spermatozoa. J Andrology, 2007
- F Haidl. Seminal parameters of chronic genital inflammation are associated with disturbed sperm DNA integrity Andrologia Jour., 2015
- S Proutski et al., Sperm DNA damage has a negative association with live birth rates after IVF. LBR., 2012
- A, Zini. Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI Systematic review and meta-analysis. Hum Reprod., 2008
- EB, Burlakova et al. Biomarkers of oxidative stress and smoking in cancer patients. J. Cancer Res. Ther., 2010
- Menezo et al. Antioxidants to reduce sperm DNA fragmentation an unexpected adverse effect, Reprod Biomed Online, 2007
- Greco et al. Reduction of the Incidence of Sperm DNA Fragmentation by Oral Antioxidant Treatment, J Androl., 2005
- www.efsa.europa.eu
- Tremellen et al. Randomised control trial examining the effect of an Antioxidant on pregnancy outcome during IVF ICSI, Aust N Z J Obstet Gynaecol., 2007
- Tremellen, Oxidative stress and male infertility—a clinical perspective: Human Reproduction Update, 2008
- Nicopoullos, et al. Sperm DNA fragmentation in subfertile men: The effect on the outcome of intracytoplactic sperm injection and correlation with sperm variables. BJU Int, 2008.
- González-Marín, J. Gosálvez, R. Roy, Types, Causes, Detection and Repair of DNA Fragmentation in Animal and Human Sperm Cells. Int J Mol Sci., 2012
- MG, Showell. et al. Antioxidants for male subfertility. Cochrane Database System Review, 2011.
- GJ, Song, et al. Relationship between seminal ascorbic acid and sperm DNA integrity in infertile men. Int J Androl, 2006
- J. Aitken and Sh. D. Roman., Antioxidant systems and oxidative stress in the testes, Oxid Med Cell Longev., 2008
- Cocuzza, S C. Sikka, K S. Athayde, A. Agarwal. Clinical Relevance of Oxidative Stress and Sperm Chromatin damage in Male Infertility: An Evidence Based Analysis, International Braz J Urol., 2007